SQL CE Excel ADODB Ruintime required?-Collection of common programming errors

If you depend on the OLEDB provider (which you do if you must run from Excel), the SQL Compact must be installed, and the OLEDB provider must be registered on the machine (requires administrator access).

So the answer to your question is No, it is not possible, unless SQL Compact 3.5 SP1 desktop runtime is already installed.

Either .NET Framework 2.0 or the SQL Compact runtime must be installed on the users PC for a DVD based setup to work with SQL Compact. If have more advice on DVD based setups here: http://erikej.blogspot.com/2009/08/running-sql-compact-from-cd-rom-read.html