BizTalk 2010 Without SQL Server. Use Oracle instead-Collection of common programming errors

Is it possible to run BizTalk 2010 without SQL Server? Or are they too tightly coupled together?

I know BizTalk has Oracle adapters, and I was hoping that I could do away witH SQL Server and have BizTalk work with our Oracle stack.

*Note. This isn’t a slam about SQL Server (I’ve had fan boys attack me on this question), but there is no need for SQL Server in our environment. The only reason we use it now is because BizTalk 2006 requires it, and we store nothing other than the bizTalk default stuff on it.